课程

课程描述

可打印版本

第一年-秋季

临床微生物学I (cls610)
This course will focus on the study of aerobic bacteria. The diagnostic techniques involved in identifying the organisms, the significance of different organisms in various clinical specimens, 将介绍微生物疾病状态和感染控制原理的应用. The student will be familiarized with the methods used for transport, 处理, identification and reporting of bacteria from specimens taken from the human body. Students will analyze and record laboratory data, comply with all safety procedures and learn to determine drug susceptibility, drug resistance and identify sources of infection. (4学分)

尿液和体液分析 (CLS 655)
本课程包括肾脏功能的医学生物化学，以及尿液分析和体液(脊髓液)的解释, 精液, 以及其他体液测试. Emphasis is on clinical significance and interpretation of laboratory results, 标本收集及保存, 生化试验程序, clinical microscopy and cytology of urine sediment. (2学分)

临床血液学与止血学 (CLS 650)
本课程将介绍在临床血液学实验室中对血细胞和体液的评估. The lecture and laboratory will highlight physiology, pathophysiology and laboratory testing of blood and bone marrow cells, 止血和止血障碍的评估和其他体液中形成元素的实验室评估. (4学分)

研究伦理(610年乙)
本课程包括基于研究过程中涉及的伦理问题的讨论形式. 学生将重点阅读研究中涉及的伦理问题，然后在讨论期间将阅读材料应用于案例研究. 涵盖的主题包括, but are not limited to: morality and 研究 ethics, ethical issues before 研究 committees, ethical issues involving human and animal subjects, reporting of 研究 and conflict of interest. (1)

Experimental Design and Data Analysis (PSC 672)
本课程是所有药学研究生的必修课，为学生提供实验设计和生物统计学的基本知识. Students will learn how to design experiments and analyze the results. The course will cover single factor experiments, 多种因素, full factorial and fractional factorial designs and screening designs, the fundamentals of hypothesis testing and relevant biostatistics. (2学分)

第一年-春季

免疫血液学(CLS 660)
免疫血液学是在实验室中将免疫学原理应用于确定适合输血的血液和血液制品以及用于移植的身体组织. The course will cover characteristics of red cell and white cell specific antigens, 献血者资格和血液处理以及自身和同种异体抗体鉴定技术对输血医学和输血服务的特定法规和质量控制要求很重要. (4学分)

临床化学(CLS 640)
这门结合讲座和实验的课程侧重于实验室仪器的基本概念, troubleshooting techniques and the operation, evaluation and selection of instruments. 讲座强调人体正常和异常代谢的生理指标的化学测量，并讨论临床化学的要素及其在患者诊断和治疗中的应用. 脂质的重要性, 碳水化合物, 蛋白质, 酶的测量, acid-base balance as they apply to diagnoses of cardiovascular, 肺, 肾脏和代谢性疾病强调通过动手测量和病理生理学的相关性. (4学分)

临床微生物学II (cls620)
This course follows similar principles as CLS610, but will focus on the study of medically relevant parasites and fungi. Students will also learn key aspects of mycological, and anaerobic infections. 通过参加CLS550和CLS560课程，学生将熟练掌握传统微生物学, as well as contemporary immune- and molecular-based identification technology. (4学分)

研究设计(BIO 650)
这门研究生水平的课程将向学生介绍生物科学中使用的研究方法. Topics to be covered include 研究 design, 数据收集和文件编制, 批判性文献综述, preparation of a NIH-style grant application, and academic presentations and publications. 课堂讨论, 研讨会, 写作作业将为学生提供实践所学研究方法的机会，并将这些方法应用于潜在论文研究项目的设计. (2学分)

临床免疫学(CLS 630)
The content of this course includes development of the immune system, immunoglobulin structure and genetics, 抗原抗体反应, the major histocompatibility complex and antigen presentation, and immune responses to infections organisms and tumors. 讲座和实验将集中于诊断技术用于识别病毒和细菌疾病和自身免疫性疾病的诊断, 过敏, 免疫缺陷和艾滋病. (4学分)

二年级-秋季

临床实习I (CLS 770)
学生将在附属医院和实验室现场参加一些体验练习. Rotations will include Clinical 微生物学, 临床化学, 免疫血液学, 血液学和凝血学, Immunology/Serology and Molecular Diagnostic testing. The clinical practicum experience will include specimen tracking, 常规分析性能, 专业测试演示, observation of automated instrumentation and management processes, including quality control and quality assurance activities. (每学期9学分)

Pre-Requisites: Completion of all required CLS 600 level courses

Advanced Good Laboratory Practices and Laboratory Management (黑洞730)
本课程为实验室人员提供良好实验室操作规范原则的培训，这些实验室人员希望产生符合目的并经得起检查审查的测试结果. This allows for the reliability, retrieval and accountability for test results.  These procedures are applicable to diagnostic laboratory procedures, 研究, forensic and in the drug safety and development sector. 主题包括安全, Clinical Laboratory Improvement Act of 1988 (CLIA) government regulations, and quality assurance in the laboratory. 学生将学习和应用管理和质量保证技能和概念，适用于不同的实验室设置, 包括标本收集, and performance per CLIA’88-and /or moderate-complexity testing. Students will also demonstrate competency in a wide variety of techniques used to collect, 工艺和试验样品. (3学分)

分子诊断学(黑洞745)
本课程是将分子概念应用于传染因子的鉴定, 疾病的遗传风险, presence and/or occurrence of mutations as a consequence of infections or toxic exposure. The use of genomic profiles as biomarkers associated with cancer and cancer risk, autoimmunity and hereditary disorders, as well as determination of histocompatability will be discussed and performed. Biotechnology as a diagnostic and investigative tool will be discussed. 在实验室学生将学习和执行基本的分子技术，如DNA和RNA分离, rt - pcr, 北方和南方的斑点. 学生还将接触到微阵列和生物信息学在医学中的应用. (4学分)

第二年-春季

Genetics and Molecular Basis of Disease (黑洞740)
本课程以了解疾病的可遗传性和/或分子基础为目标，奠定基本遗传学概念的基础. 最近的证据和诊断程序表明，遗传性疾病在儿科和成人人口的总疾病负担中占很大比例. 今天的卫生保健从业者和生物医学科学家必须了解医学遗传学的科学和改变基因组学和蛋白质组学的后果. 诊断遗传性疾病的新的和更准确的方法的发展取得了进展，导致了更大的“遗传意识”，并认识到遗传学在医学的所有领域都发挥着作用. 它将使用广泛的例子来说明在地中海贫血中发现的突变的影响, 镰状细胞性贫血, 囊性纤维化, familial Amyotrophic Lateral Sclerosis and Huntington’s Disease as causes of disease. It will also discuss genetics as a predisposing factor, such as in the case of birth defects, 乳腺癌, 阿尔茨海默病, alcoholism and some   autoimmune disorders. 环境诱导的突变和癌变以及癌基因和肿瘤抑制基因的作用将是本课程后半部分的重点. (4学分)

Pre-Requisites: CHE 311/312 or equivalent

临床实习II (CLS 780)
学生将在附属医院和实验室现场参加一些体验练习. Rotations will include Clinical 微生物学, 临床化学, 免疫血液学, 血液学和凝血学, Immunology/Serology and Molecular Diagnostic testing. The clinical practicum experience will include specimen tracking, 常规分析性能, 专业测试演示, observation of automated instrumentation and management processes, including quality control and quality assurance activities. (9学分)

Pre-Requisites: Completion of all required CLS 600 level courses

临床相关性(cls760)
学生将评估一系列案例研究，这些案例研究整合了实验室诊断医学的所有学科. The cases will require knowledge of laboratory test result normal, factors that affect the accuracy of laboratory test results, 质量管理原则, and the ability to integrate diverse information to arrive at a diagnosis, corrective action or quality improvement recommendation. (3学分)

先决条件:CLS 780

顶石(黑洞790)
顶点项目是一个最终的经验，混合诊断实验室实践和临床研究的各个方面. Students will demonstrate the ability to read and analyze scientific literature, formulate case studies or project topics, 为口头报告准备研究结果，并在期末论文或海报展示中完成文献综述. (3学分)